认识和联系Profil的专家

Oliver Klein 科学研究顾问 Oliver是您在以下领域的联系伙伴: 胰腺钳夹 稳定同位素/代谢通量

简介

Oliver是一位具有内科临床背景的医生，他在糖尿病领域临床研究项目的开发、实施和评估方面拥有14年经验。

他的特别研究兴趣是胰岛素药理学和代谢研究方法。

他是Profil诺伊斯的科学研究顾问。

发表物

以下是Oliver的近期发表物:

• Leohr J, Dellva MA, LaBell E, Coutant DE, Klein O, Plum-Moerschel L, Zijlstra E, Linnebjerg H.
  Pharmacokinetic and glucodynamic responses of ultra rapid lispro vs lispro across a clinically relevant range of subcutaneous doses in healthy subjects.
  Clin Ther 42: 1762-1777, 2020
• Meiffren G, Herbrand T, Anastassiadis E, Klein O, DeVries JH, Heise T, Alluis B, Megret C, Gaudier M, Soula O, Plum-Mörschel L.
  Better glycemic control with BioChaperone Combo (BC Combo) than with insulin lispro Mix25 (LMix) or separate glargine & lispro (G+L) administrations after a test meal in subjects with type 2 diabetes (T2DM).
  DIABETES OBES METAB 2019 Mar 3. doi: 10.1111/dom.13685. (Epub ahead of print)
• Heise T, Meiffren G, Alluis B, Seroussi C, Ranson A, Arrubla J, Correia J, Gaudier M, Soula O, Soula R, DeVries JH, Klein O, Bode B.
  BioChaperone Lispro versus faster aspart and insulin aspart in patients with type 1 diabetes using continuous subcutaneous insulin infusion: A randomized euglycemic clamp study.
  DIABETES OBES METAB 2018 Dec 18. doi: 10.1111/dom. 13621. (Epub ahead of print)
• Benesch C, Heise T, Klein O, Heinemann L, Arnolds S.
  How to assess the quality of glucose clamps? Evaluation of clamps performed with ClampArt, a novel automated clamp device.
  J DIABETES SCI TECHNOL 9: 792-800, 2015.
• Heise T, Nosek L, Klein O, Coester H, Svendsen AL, Haahr H.
  Insulin degludec/insulin aspart produces a dose-proportional glucose-lowering effect in subjects with type 1 diabetes mellitus.
  DIABETES OBES METAB 17: 659-664, 2015.
• Heise T, Nosek L, Roepstorff C, Chenji S, Klein O, Haahr H.Distinct prandial and basal glucose-lowering effects of insulin degludec/insulin aspart (IDegAsp) at steady state in subjects with type 1 diabetes mellitus.
  DIABETES THER 5 (1): 255-265, 2014

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主要成就及工作经验