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Dr. Carsten Benesch Director Technical Development Carsten is heading the ClampArt development activities. He is your contact partner, among others, for the following areas: ClampArt Artificial pancreas projects Other technology issues

Short Bio

Carsten is a physicist in the field of nano-structured surfaces on condensed matter and has long-term experience in hardware and software development of medical devices. At Profil he is the Director of Technical Development and manager of the AP@home EU project.

Core Competence Areas

Technical development of medical devices

Publications

Here are Carsten's recent publications:

• Benesch C, Kuhlenkötter M, Nosek L, Heise T.
  New Clamp-PID Algorithm for automated glucose clamps improves clamp quality.
  J Diabetes Sci Technol 2021 Feb 10. doi: 10.1177/1932296821991514
• Leelarathna L, Thabit H, Wilinska ME, Bally L, Mader JK, Pieber TR, Benesch C, Arnolds S, Johnson T, Heinemann L, Hermanns N, Evans ML, Hovorka R.
  Evaluating glucose control with a novel composite continuous glucose monitoring index.
  J DIABETES SCI TECHNOL 2019 MAR 31. doi: 10.1177/1932296819838525. (Epub ahead of print)
• Benesch C, Kuhlenkötter M, Heise T.
  Considering blood dilution improves the precision of continuous whole blood glucose measurements.
  J DIABETES SCI TECHNOL 2018 Sep 26. doi: 10.1177/1932296818803621. (Epub ahead of print)
• Schliess F, Heise T, Benesch C, Mianowska B, Stegbauer C, Broge B, Gillard P, Binkley G, Crone V, Carlier S, Delval C, Petkov A, Beck JP, Lodwig V, Gurdala M, Szecsenyi J, Rosenmöller M, Cypryk K, Mathieu C, Renard E, Heinemann L.
  Artificial pancreas systems for people with type 2 diabetes: Conception and design of the European CLOSE project.
  J Diabetes Sci Technol 2018 Sep 21. doi: 10.1177/1932296818803588. (Epub ahead of print)
• Ruan Y, Bally L, Thabit H, Leelarathna L, Hartnell S, Tauschmann M, Wilinska ME, Evans ML, Kojzar H, Dellweg S, Benesch C, Arnolds S, Pieber TR, Hovorka R.
  Hypoglycaemia incidence and recovery during home use of hybrid closed-loop insulin delivery in adults with type 1 diabetes.
  DIABETES OBES METAB 2018 Mar 25. doi: 10.1111/dom.13304. (Epub ahead of print)
• Bally L, Thabit H, Ruan Y, Mader JK, Kojzar H, Dellweg S, Benesch C, Hartnell S, Leelarathna L, Wilinska ME, Evans ML, Arnolds S, Pieber TR, Hovorka R.
  Bolusing frequency and amount impacts glucose control during hybrid closed-loop.
  DIABET MED 2017 Jul 29. doi: 10.1111/dme.13436. (Epub ahead of print)
• Emami A, Wilinska ME, Thabit H, Leelarathna L, Dellweg S, Benesch C, Mader JK, Holzer M, Kojzar H, Pieber TR, Arnolds S, Evans ML, Hovorka R.
  Behavioral patterns and associations with glucose control during 12-week randomized free-living clinical trial of day and night hybrid closed-loop insulin delivery in adults with type 1 diabetes.
  DIABETES TECHNOL THER 2017 May 2. doi: 10.1089/dia.2016.0307. (Epub ahead of print)
• Barnard KD, Wysocki T, Ully V, Mader JK, Pieber TR, Thabit H, Tauschmann M, Leelarathna L, Hartnell S, Acerini CL, Wilinska ME, Dellweg S, Benesch C, Arnolds S, Holzer M, Kojzar H, Campbell F, Yong J, Picchierri J, Hindmarsh P, Heinemann L, Evans ML, Hovorka R.
  Closing the loop in adults, children and adolescents with suboptimally controlled type 1 diabetes under free living conditions: A psychosocial substudy.
  J DIABETES SCI TECHNOL 2017 Apr 1. doi: 10.1177/1932296817702656. (Epub ahead of print)
• Ruan Y, Thabit H, Leelarathna L, Hartnell S, Wilinska ME, Tauschmann M, Dellweg S, Benesch C, Mader JK, Holzer M, Kojzar H, Evans ML, Pieber TR, Arnolds S, Hovorka R on behalf of AP@home consortium.
  Faster insulin action is associated with improved outcomes during closed-loop insulin delivery and sensor-augmented pump therapy in adults with type 1 diabetes.
  DIABETES OBES METAB 2017. doi: 10.1111/dom.12956 (Epub ahead of print)
• Kuhlenkötter M, Heise T, Benesch C.
  Improved algorithm for automated glucose clamps.
  DIABETES TECHNOL THER 19: 124-130, 2017 
• Leelarathna L, Thabit H, Hartnell S, Wilinska ME, Dellweg S, Benesch C, Mader JK, Holzer M, Kojzar H, Evans ML,
  Arnolds S, Pieber TR, Hovorka R, on behalf of the AP@home Consortium.
  Rapid benefits of structured optimization and sensor-augmented insulin pump therapy in adults with type 1 diabetes.
  J DIABETES SCI TECHNOL 11: 180-181, 2017
• Ruan Y, Thabit H, Leelarathna L, Hartnell S, Wilinska ME, Dellweg S, Benesch C, Mader JK, Holzer M, Kojzar H, Evans ML, Pieber TR, Arnolds S, Hovorka R, on behalf of the AP@home Consortium.
  Variability of insulin requirements over 12 weeks of closed-loop insulin delivery in adults with type 1 diabetes.
  DIABETES CARE 39: 830-832, 2016
• Thabit H, Tauschmann M, Allen JM, Leelarathna L, Hartnell S, Wilinska ME, Acerini CL, Dellweg S, Benesch C, Heinemann L, Mader JK, Holzer M, Kojzar H, Exall J, Yong J, Pichierri J, Barnard KD, Kollman C, Cheng P, Hindmarsh PC, Campbell FM, Arnolds S, Pieber TR, Evans ML, Dunger DB, Hovorka R; APCam Consortium and AP@home Consortium.
  Home use of an artificial beta cell in type 1 diabetes
  N ENGL J MED 2015 Sep 17. doi: 10.1056/NEJMoa1509351. (Epub ahead of print)
• Thabit H, Leelarathna L, Wilinska ME, Elleri D, Allen JM, Lubina-Solomon A, Walkinshaw E, Stadler M, Choudhary P, Mader JK, Dellweg S, Benesch C, Pieber TR, Arnolds S, Heller SR, Amiel SA, Dunger D, Evans ML, Hovorka R.
  Accuracy of continuous glucose monitoring during three closed-loop home studies under free-living conditions.
  DIABETES TECHNOL THER 17: 801-807, 2015
• Benesch C, Heise T, Klein O, Heinemann L, Arnolds S.
  How to assess the quality of glucose clamps? Evaluation of clamps performed with ClampArt, a novel automated clamp device.
  J DIABETES SCI TECHNOL 9: 792-800, 2015.
• Leelarathna L, Dellweg S, Mader JK, Allen JM, Benesch C, Doll W, Ellmerer M, Hartnell S, Heinemann L, Kojzar H, Michalewski L, Nodale M, Thabit H, Wilinska ME, Pieber TR, Arnolds S, Evans ML, Hovorka R, on behalf of the AP@home Consortium.
  Day and night home closed-loop insulin delivery in adults with type 1 diabetes: three-center randomized crossover study.
  DIABETES CARE 37: 1931-1937, 2014
• Luijf YM, Arnolds S, Avogaro A, Benesch C, Bruttomesso D, Farret A, Heinemann L, Place J, Renard E, Scotton R, DeVries JH, on behalf of the AP@home consortium.
  Patch pump versus conventional pump: Postprandial glycemic excursions and the influence of wear time.
  DIABETES TECHNOL THER 15: 575-579, 2013
• Luijf YM, Mader JK, Doll W, Pieber T, Farret A, Place J, Renard E, Bruttomesso D, Filippi A, Avogaro A, Arnolds S, Benesch C, Heinemann L, DeVries JH, on behalf of the AP@home consortium.
  Accuracy and reliability of continuous glucose monitoring systems: a head-to-head comparison.
  DIABETES TECHNOL THER 15: 722-727, 2013
• Luijf YM, DeVries JH, Zwinderman K, Leerathna L, Nodale M, Caldwell K, Kumareswaran K, Elleri D, Allen JM, Wilinska ME, Evans ML, Hovorka R, Doll W, Ellmerer M, Mader JK, Renard E, Place J, Farret A, Cobelli C, Del Favero S, Dalla Man C, Avogaro A, Bruttomesso D, Filippi A, Scotton R, Magni L, Lanzola G, Di Palma F, Toffanin C, Arnolds S, Benesch C, Heinemann L, on behalf of the AP@home consortium.
  Day and night closed-loop control in adults with type 1 diabetes mellitus.
  DIABETES CARE 36: 3882-3887, 2013
• Facchinetti A, Sparacino G, Guerra S, Luijf M, De Vries JH, Mader JK, Ellmerer M, Benesch C, Heinemann L, Bruttomesso D, Avogaro A, Cobelli C.
  Real-time improvement of continuous glucose-monitoring accuracy: the smart sensor concept.
  DIABETES CARE PMID: 23172973 (Epub ahead of print), 2012
• Luijf YM, Avogaro A, Benesch C, Bruttomesso D, Cobelli C, Ellmerer M, Heinemann L, Mader JK, De Vries JH.
  Continuous glucose monitoring accuracy results vary between assessment at home and assessment at the clinical research center.
  J DIABETES SCI TECHNOL. 6(5): 1103-1106, 2012

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Selected Achievements and Work Experience